CITMIC: Estimation of Cell Infiltration Based on Cell Crosstalk

A systematic biology tool was developed to identify cell infiltration via Individualized Cell-Cell interaction network. 'CITMIC' first constructed a weighted cell interaction network through integrating Cell-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells.

Version:	0.1.0
Depends:	R (≥ 2.10)
Imports:	fastmatch, igraph, parallel, stats
Suggests:	knitr, rmarkdown
Published:	2024-06-14
DOI:	10.32614/CRAN.package.CITMIC
Author:	Junwei Han [aut, cre, cph], Xilong Zhao [aut]
Maintainer:	Junwei Han <hanjunwei1981 at 163.com>
License:	GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation:	no
CRAN checks:	CITMIC results

Documentation:

Reference manual:	CITMIC.pdf
Vignettes:	CITMIC User Guide

Downloads:

Package source:	CITMIC_0.1.0.tar.gz
Windows binaries:	r-devel: CITMIC_0.1.0.zip, r-release: CITMIC_0.1.0.zip, r-oldrel: CITMIC_0.1.0.zip
macOS binaries:	r-release (arm64): CITMIC_0.1.0.tgz, r-oldrel (arm64): CITMIC_0.1.0.tgz, r-release (x86_64): CITMIC_0.1.0.tgz, r-oldrel (x86_64): CITMIC_0.1.0.tgz

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